Nuuk, Greenland - Locals frequent a shopping centre in Nuuk, Greenland, March 2016. Nuuk is the capital and largest city of Greenland. It is the seat of government and the country's largest cultural and economic centre. The major cities closest to the capital are Iqaluit and St. John's in Canada and Reykjavík in Iceland. Nuuk contains almost a quarter of Greenland's population, and also has the tallest building in Greenland. Nuuk is the seat of government for the Sermersooq municipality. In January 2016, it had a population of 17,316.